Uloric is a prescription medication used to treat gout. It is a xanthine oxidase inhibitor. The medication is designed to lower the level of blood uric acid in patients suffering from gout. Patients should keep in mind that Uloric is only for adults as it is not understood if the drug is safe or effective for children under 18. The drug is used to prevent further gout attacks. Uloric does not treat gout symptoms as they occur. The drug was approved by the Food and Drug Administration in 2009. It is manufactured by Takeda Pharmaceuticals Inc.
Patients should not take Uloric while taking either of the following:
- Azathioprine (Imuran, Azasan)
- Mercaptopurine (Purinethol)
- Uniphyl, Theodur, Theochron (theophylline)
Prior to taking Uloric, patients should consult their healthcare provider. Additionally, patients should let them know about any prior conditions. The following is especially important:
- Issues relating to stroke or heart disease.
- Any problems with the liver or kidney.
- Pregnant or planning to become pregnant. Studies are not sure if the drug can cause damage to the fetus.
- Breastfeeding. Medical researchers are still unsure whether the drug can be transmitted in breast milk.
Patients can discuss all their concerns with a physician and should also let them know about any prescription or non-prescription drugs they are taking. This includes any vitamins, supplements, or alternative medicines. Uloric may be affected by either a pre-existing medical condition or prescription drugs a patient is currently taking.
Before talking to a physician, take note of everything listed above and then be ready to discuss it.
Method of Ingestion
You should take Uloric according to the directions outlined by a physician. Patients can take the drug with food or without. While taking the drug, a physician may ask patients to undergo specific tests. Patients can also take the drug alongside antacids. If gout symptoms flare up while taking Uloric, do not stop taking the drug as this is to be expected.
Uloric can take up to several months before the drug begins preventing gout flare-ups. Physicians may provide further medication to alleviate the symptoms and prevent more gout flares.
How to Store Uloric
It is recommended that Uloric is stored away from direct sunlight and the reach of children. It should also be stored between 59 and 86 degrees Fahrenheit.
Uloric should only be used for the medication’s intended purpose and should not be shared with other patients with gout symptoms.
What is in Uloric?
Uloric contains the active ingredient febuxostat. Febuxostat is considered a non-hygroscopic. It is a white crystalline powder which is soluble in dimethylformamide. The inactive ingredients include magnesium stearate, silicon dioxide, sodium croscarmellose, hydroxypropyl cellulose, microcrystalline cellulose, and lactose monohydrate.
Uloric is available in two dosages. It either comes in Uloric 40 mg or Uloric 80 mg tablets and is to be consumed orally. Uloric is protected by a coating that contains Opadry II. Patients should always take the dosage as directed by doctors and pharmacists. Patients who miss out on a dose should take the medication as soon as possible but be careful not to double up. It is recommended that patients skip the missed dose if it is close to the time for the next dose. Taking extra Uloric to make up for a missed dosage is never a good idea.
Side Effects of Uloric
Uloric has a number of known side effects. During clinical studies of the drug, a small number of strokes and heart-related issues occurred.
Some of Uloric’s known side effects are:
- Skin irritation or rashes
- Joint pain
- Flaring of gout
- Liver issues
- Motor issues
- Appetite loss
- Change in urine or stool
- Migraines or headaches
- Pain in either your arm or shoulder
- Weakness or numbness in your body
Patients experiencing any of the above Uloric side effects should immediately contact their doctor, especially if they persist over a period of days.
Severe Side Effects of Uloric
The U.S. Food and Drug Administration (FDA) recently ordered a black box warning for Uloric after research showed that the drug’s health-related side effects outweigh the benefits. Studies have found that Uloric increases the risk of death and cardiovascular issues.
A Black Box warning from the FDA is considered to be the most serious label warning. Patients taking Uloric should understand that the medication has severe side effects. In a study performed by Takeda Pharmaceuticals with 6,000 patients taking Uloric, some patients suffered:
- Inadequate Blood Supply To Their Heart
- Non-Fatal Stroke
- Non-Fatal Heart Attack
Other serious Uloric side effects include:
- Cardiac Death
- Heart Attack
- Liver Enzyme Abnormalities
- Numbness In Extremities
- Myocardial Infarction
- Liver Failure
- Kidney Failure
Contact a Professional Drug Injury Lawyer
The Eichholz Law Firm understands the complexities within a dangerous drug and product liability lawsuit. If you or a loved one has suffered health-related injuries due to the negligence of Takeda Pharmaceuticals and their dangerous drug, you may be entitled to a Uloric lawsuit.
Victims of Uloric can trust the lawyers from The Eichholz Law Firm because we are committed to fighting for justice and helping our clients receive the compensation that they deserve.
- FDA. “FDA adds Boxed Warning for increased risk of death with gout medicine Uloric (febuxostat)“, U.S. Department of Health and Human Services, https://www.fda.gov/Drugs/DrugSafety/ucm631182.htm. Accessed March 8, 2019.
- RxList. “Uloric“, RxList, https://www.rxlist.com/uloric-drug.htm. Accessed March 12, 2019.
- WebMD. “Uloric Side Effects by Likelihood and Severity“, WebMD, https://www.webmd.com/drugs/2/drug-151872/uloric-oral/details/list-sideeffects. Accessed March 18, 2019.